Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis

Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis

Despite the fact that the majority of lung cancer deaths are due to metastasis, the molecular mechanisms driving metastatic progression are poorly understood. Here, we present evidence that loss of Foxa2 and Cdx2 synergizes with loss of Nkx2-1 to fully activate the metastatic program. These three li...

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Bibliographic Details
Main Authors: Li, Carman Man-Chung, Gocheva, Vasilena, Wang, Shi Yun, Date, Saya R., Ng, Sheng Rong, Whittaker, Charles A., Bronson, Roderick T., Snyder, Eric L., Oudin, Madeleine Julie, Gertler, Frank, Bhutkar, Arjun, Jacks, Tyler E
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Cold Spring Harbor Laboratory Press 2016
Online Access:http://hdl.handle.net/1721.1/102087
https://orcid.org/0000-0001-6988-4260
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0003-1655-2443
https://orcid.org/0000-0003-3214-4554
https://orcid.org/0000-0002-7799-6454

Internet

http://hdl.handle.net/1721.1/102087
https://orcid.org/0000-0001-6988-4260
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0003-1655-2443
https://orcid.org/0000-0003-3214-4554
https://orcid.org/0000-0002-7799-6454

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