Optogenetic drive of neocortical pyramidal neurons generates fMRI signals that are correlated with spiking activity

Local fluctuations in the blood oxygenation level-dependent (BOLD) signal serve as the basis of functional magnetic resonance imaging (fMRI). Understanding the correlation between distinct aspects of neural activity and the BOLD response is fundamental to the interpretation of this widely used mappi...

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Bibliographic Details
Main Authors: Kahn, I., Knoblich, Ulf, Desai, Mitul, Bernstein, Jacob G., Moore, Christopher I., Buckner, R. L., Graybiel, Ann M, Boyden, Edward
Other Authors: Massachusetts Institute of Technology. Synthetic Neurobiology Group
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/102221
https://orcid.org/0000-0002-7472-5480
https://orcid.org/0000-0002-0419-3351
https://orcid.org/0000-0002-8381-7555
https://orcid.org/0000-0002-0756-5587
https://orcid.org/0000-0002-4326-7720