Stent elution rate determines drug deposition and receptor-mediated effects
Drug eluting stent designs abound and yet the dependence of efficacy on drug dose and elution duration remains unclear. We examined these issues within a mathematical framework of arterial drug distribution and receptor binding following stent elution. Model predictions that tissue content linearly...
Main Authors: | , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2016
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Online Access: | http://hdl.handle.net/1721.1/102303 https://orcid.org/0000-0002-7832-7156 |