The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)
Fragile X is the most common known inherited cause of intellectual disability and autism, and it typically results from transcriptional silencing of FMR1 and loss of the encoded protein, FMRP (fragile X mental retardation protein). FMRP is an mRNA-binding protein that functions at many synapses to i...
| Autores principales: | , , |
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| Otros Autores: | |
| Formato: | Artículo |
| Lenguaje: | en_US |
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Annual Reviews
2016
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| Acceso en línea: | http://hdl.handle.net/1721.1/102333 |