Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

Tet1 Is Critical for Neuronal Activity-Regulated Gene Expression and Memory Extinction

The ten-eleven translocation (Tet) family of methylcytosine dioxygenases catalyze oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and promote DNA demethylation. Despite the abundance of 5hmC and Tet proteins in the brain, little is known about the functions of the neuronal Tet...

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Bibliographic Details
Main Authors: Rudenko, Andrii, Dawlaty, Meelad M., Seo, Jinsoo, Cheng, Albert W., Meng, Jia, Le, Thuc, Faull, Kym F., Jaenisch, Rudolf, Tsai, Li-Huei
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/102511
https://orcid.org/0000-0003-1262-0592

Internet

http://hdl.handle.net/1721.1/102511
https://orcid.org/0000-0003-1262-0592

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