In vivo genome editing using Staphylococcus aureus Cas9

In vivo genome editing using Staphylococcus aureus Cas9

The RNA-guided endonuclease Cas9 has emerged as a versatile genome-editing platform. However, the size of the commonly used Cas9 from Streptococcus pyogenes (SpCas9) limits its utility for basic research and therapeutic applications that use the highly versatile adeno-associated virus (AAV) delivery...

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Bibliographic Details
Main Authors: Ran, F. Ann, Cong, Le, Yan, Winston X., Gootenberg, Jonathan S., Kriz, Andrea J., Zetsche, Bernd, Shalem, Ophir, Wu, Xuebing, Makarova, Kira S., Koonin, Eugene V., Sharp, Phillip A., Zhang, Feng, Yan, Winston Xia, Scott, David Arthur
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/102586
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0003-1465-1691
https://orcid.org/0000-0002-3067-479X
https://orcid.org/0000-0002-2639-9879
https://orcid.org/0000-0003-0369-5269

Internet

http://hdl.handle.net/1721.1/102586
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0003-1465-1691
https://orcid.org/0000-0002-3067-479X
https://orcid.org/0000-0002-2639-9879
https://orcid.org/0000-0003-0369-5269

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