Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors

Chronic exposure to drugs of abuse or stress regulates transcription factors, chromatin-modifying enzymes and histone post-translational modifications in discrete brain regions. Given the promiscuity of the enzymes involved, it has not yet been possible to obtain direct causal evidence to implicate...

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Bibliographic Details
Main Authors: Sun, Haosheng, Shao, Ningyi, Feng, Jian, Mazei-Robison, Michelle, Ferguson, Deveroux, Knight, Scott, Nievera, Christian, Han, Ming-Hu, Shen, Li, Zhang, H Steve, Zhang, Feng, Nestler, Eric J, Heller, Elizabeth A., Cates, Hannah M., Pena, Catherine J., Golden, Sam A., Herman, James P., Walsh, Jessica J., Gerber, Mark A., Russo, Scott J., Tamminga, Carol S., Neve, Rachael L.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/102587
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0002-3854-5968