Locus-specific epigenetic remodeling controls addiction- and depression-related behaviors
Chronic exposure to drugs of abuse or stress regulates transcription factors, chromatin-modifying enzymes and histone post-translational modifications in discrete brain regions. Given the promiscuity of the enzymes involved, it has not yet been possible to obtain direct causal evidence to implicate...
Main Authors: | Sun, Haosheng, Shao, Ningyi, Feng, Jian, Mazei-Robison, Michelle, Ferguson, Deveroux, Knight, Scott, Nievera, Christian, Han, Ming-Hu, Shen, Li, Zhang, H Steve, Zhang, Feng, Nestler, Eric J, Heller, Elizabeth A., Cates, Hannah M., Pena, Catherine J., Golden, Sam A., Herman, James P., Walsh, Jessica J., Gerber, Mark A., Russo, Scott J., Tamminga, Carol S., Neve, Rachael L. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2016
|
Online Access: | http://hdl.handle.net/1721.1/102587 https://orcid.org/0000-0003-2782-2509 https://orcid.org/0000-0002-3854-5968 |
Similar Items
-
SIRT1-FOXO3a Regulate Cocaine Actions in the Nucleus Accumbens
by: Ferguson, Deveroux, et al.
Published: (2015) -
Essential Role of SIRT1 Signaling in the Nucleus Accumbens in Cocaine and Morphine Action
by: Ferguson, Deveroux, et al.
Published: (2014) -
Behavioral and Structural Responses to Chronic Cocaine Require a Feedforward Loop Involving ΔFosB and Calcium/Calmodulin-Dependent Protein Kinase II in the Nucleus Accumbens Shell
by: Neve, Rachael L., et al.
Published: (2013) -
A Novel Role of the WNT-Dishevelled-GSK3β Signaling Cascade in the Mouse Nucleus Accumbens in a Social Defeat Model of Depression
by: Wilkinson, Matthew B., et al.
Published: (2012) -
∆FosB differentially modulates nucleus accumbens direct and indirect pathway function
by: Neve, Rachael L., et al.
Published: (2013)