Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity

Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity

Long-term memory formation is known to be critically dependent upon de novo gene expression in the brain. As a consequence, pharmacological enhancement of the transcriptional processes mediating long-term memory formation provides a potential therapeutic strategy for cognitive disorders involving ab...

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Bibliographic Details
Main Authors: Fass, Daniel M., Reis, Surya A., Ghosh, Balaram, Hennig, Krista M., Joseph, Nadine F., Zhao, Wen-Ning, Nieland, Thomas J.F., Guan, Ji-Song, Groves Kuhnle, Chelsea E., Tang, Weiping, Barker, Douglas D., Mazitschek, Ralph, Schreiber, Stuart L., Tsai, Li-Huei, Haggarty, Stephen J.
Other Authors: Picower Institute for Learning and Memory
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/102663
https://orcid.org/0000-0003-1262-0592

Internet

http://hdl.handle.net/1721.1/102663
https://orcid.org/0000-0003-1262-0592

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