The schizophrenia risk gene product miR-137 alters presynaptic plasticity
Noncoding variants in the human MIR137 gene locus increase schizophrenia risk with genome-wide significance. However, the functional consequence of these risk alleles is unknown. Here we examined induced human neurons harboring the minor alleles of four disease-associated single nucleotide polymorph...
Main Authors: | Siegert, Sandra, Seo, Jinsoo, Kwon, Ester, Rudenko, Andrii, Cho, Sukhee, Wang, Wenyuan, Flood, Zachary, Martorell, Anthony, Ericsson, Maria, Mungenast, Alison, Tsai, Li-Huei |
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Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2016
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Online Access: | http://hdl.handle.net/1721.1/102680 https://orcid.org/0000-0002-2206-2590 https://orcid.org/0000-0003-1262-0592 https://orcid.org/0000-0001-8635-0877 https://orcid.org/0000-0002-6335-9681 |
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