Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains

Transcription activator-like effectors are sequence-specific DNA-binding proteins that harbour modular, repetitive DNA-binding domains. Transcription activator-like effectors have enabled the creation of customizable designer transcriptional factors and sequence-specific nucleases for genome enginee...

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Bibliographic Details
Main Authors: Cong, Le, Zhou, Ruhong, Kuo, Yu-chi, Cunniff, Margaret Mary, Zhang, Feng
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/102685
https://orcid.org/0000-0003-2782-2509