Multiplex Genome Engineering Using CRISPR/Cas Systems

Multiplex Genome Engineering Using CRISPR/Cas Systems

Functional elucidation of causal genetic variants and elements requires precise genome editing technologies. The type II prokaryotic CRISPR (clustered regularly interspaced short palindromic repeats)/Cas adaptive immune system has been shown to facilitate RNA-guided site-specific DNA cleavage. We en...

Full description

Bibliographic Details
Main Authors: Cong, Le, Ran, F. Ann, Cox, David Daniel, Lin, Shuailiang, Barretto, Robert, Habib, Naomi, Hsu, Patrick, Wu, Xuebing, Jiang, Wenyan, Marraffini, Luciano A., Zhang, Feng
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2016
Online Access:http://hdl.handle.net/1721.1/102687
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0002-2189-9743

Internet

http://hdl.handle.net/1721.1/102687
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0002-2189-9743

Similar Items