Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe

Eukaryotic genomes are folded into three-dimensional structures, such as self-associating topological domains, the borders of which are enriched in cohesin and CCCTC-binding factor (CTCF) required for long-range interactions. How local chromatin interactions govern higher-order folding of chromatin...

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Bibliographic Details
Main Authors: Mizuguchi, Takeshi, Fudenberg, Geoffrey, Mehta, Sameet, Belton, Jon-Matthew, Taneja, Nitika, Folco, Hernan Diego, FitzGerald, Peter, Dekker, Job, Mirny, Leonid A., Barrowman, Jemima, Grewal, Shiv I. S.
Other Authors: Institute for Medical Engineering and Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/103055
https://orcid.org/0000-0002-0785-5410
https://orcid.org/0000-0001-5905-6517