Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite

Plasmodium knowlesi is a zoonotic parasite transmitted from macaques causing malaria in humans in Southeast Asia. Plasmodium parasites bind to red blood cell (RBC) surface receptors, many of which are sialylated. While macaques synthesize the sialic acid variant N-glycolylneuraminic acid (Neu5Gc), h...

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Bibliographic Details
Main Authors: Dankwa, Selasi, Lim, Caeul, Bei, Amy K., Jiang, Rays H. Y., Abshire, James Robbins, Patel, Saurabh D., Goldberg, Jonathan M., Moreno, Yovany, Kono, Maya, Niles, Jacquin C., Duraisingh, Manoj T.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Springer Nature 2016
Online Access:http://hdl.handle.net/1721.1/103124
https://orcid.org/0000-0002-6250-8796

Internet

http://hdl.handle.net/1721.1/103124
https://orcid.org/0000-0002-6250-8796

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