Reconstructing Causal Biological Networks through Active Learning

Reverse-engineering of biological networks is a central problem in systems biology. The use of intervention data, such as gene knockouts or knockdowns, is typically used for teasing apart causal relationships among genes. Under time or resource constraints, one needs to carefully choose which interv...

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Bibliographic Details
Main Authors: Cho, Hyunghoon, Berger Leighton, Bonnie, Peng, Jian
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Public Library of Science 2016
Online Access:http://hdl.handle.net/1721.1/103281
https://orcid.org/0000-0002-2713-0150
https://orcid.org/0000-0002-2724-7228