Spatial signals link exit from mitosis to spindle position

In budding yeast, if the spindle becomes mispositioned, cells prevent exit from mitosis by inhibiting the mitotic exit network (MEN). The MEN is a signaling cascade that localizes to spindle pole bodies (SPBs) and activates the phosphatase Cdc14. There are two competing models that explain MEN regul...

Full description

Bibliographic Details
Main Authors: Falk, Jill, Tsuchiya, Dai, Verdaasdonk, Jolien, Lacefield, Soni, Bloom, Kerry, Amon, Angelika B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: eLife Sciences Publications, Ltd. 2016
Online Access:http://hdl.handle.net/1721.1/103533
https://orcid.org/0000-0003-2910-9803
https://orcid.org/0000-0001-9837-0314