Post-translational control of genetic circuits using Potyvirus proteases

Genetic engineering projects often require control over when a protein is degraded. To this end, we use a fusion between a degron and an inactivating peptide that can be added to the N-terminus of a protein. When the corresponding protease is expressed, it cleaves the peptide and the protein is degr...

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Bibliographic Details
Main Authors: Fernandez-Rodriguez, Jesus, Voigt, Christopher A.
Other Authors: MIT Synthetic Biology Center
Format: Article
Language:en_US
Published: Oxford University Press 2016
Online Access:http://hdl.handle.net/1721.1/103544
https://orcid.org/0000-0003-0844-4776
https://orcid.org/0000-0002-6469-0229