Post-translational control of genetic circuits using Potyvirus proteases
Genetic engineering projects often require control over when a protein is degraded. To this end, we use a fusion between a degron and an inactivating peptide that can be added to the N-terminus of a protein. When the corresponding protease is expressed, it cleaves the peptide and the protein is degr...
Main Authors: | Fernandez-Rodriguez, Jesus, Voigt, Christopher A. |
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Other Authors: | MIT Synthetic Biology Center |
Format: | Article |
Language: | en_US |
Published: |
Oxford University Press
2016
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Online Access: | http://hdl.handle.net/1721.1/103544 https://orcid.org/0000-0003-0844-4776 https://orcid.org/0000-0002-6469-0229 |
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