Compaction and segregation of sister chromatids via active loop extrusion
The mechanism by which chromatids and chromosomes are segregated during mitosis and meiosis is a major puzzle of biology and biophysics. Using polymer simulations of chromosome dynamics, we show that a single mechanism of loop extrusion by condensins can robustly compact, segregate and disentangle c...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
eLife Sciences Publications, Ltd.
2016
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| Online Access: | http://hdl.handle.net/1721.1/103581 https://orcid.org/0000-0002-0785-5410 https://orcid.org/0000-0002-5320-2728 https://orcid.org/0000-0002-2210-8616 |