Optogenetic activation of intracellular adenosine A[subscript 2A] receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory
Human and animal studies have converged to suggest that caffeine consumption prevents memory deficits in aging and Alzheimer’s disease through the antagonism of adenosine A2A receptors (A2ARs). To test if A2AR activation in the hippocampus is actually sufficient to impair memory function and to begi...
Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Language: | en_US |
Published: |
Nature Publishing Group
2016
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Online Access: | http://hdl.handle.net/1721.1/103590 https://orcid.org/0000-0002-0419-3351 |