Characterization of the expression of the pro-metastatic MenaINV isoform during breast tumor progression

Characterization of the expression of the pro-metastatic MenaINV isoform during breast tumor progression

Several functionally distinct isoforms of the actin regulatory Mena are produced by alternative splicing during tumor progression. Forced expression of the Mena[superscript INV] isoform drives invasion, intravasation and metastasis. However, the abundance and distribution of endogenously expressed M...

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Detalhes bibliográficos
Principais autores: Rohani, Nazanin, Moufarrej, Mira N., Jones, Joan G., Condeelis, John S., Gertler, Frank B., Oudin, Madeleine Julie, Gertler, Frank, Hughes-Alford, Shannon Kay, Lauffenburger, Douglas A
Outros Autores: Massachusetts Institute of Technology. Department of Biological Engineering
Formato: Artigo
Idioma:English
Publicado em: Springer Netherlands 2016
Acesso em linha:http://hdl.handle.net/1721.1/103617
https://orcid.org/0000-0001-6988-4260
https://orcid.org/0000-0003-3214-4554
https://orcid.org/0000-0003-3916-6115

Internet

http://hdl.handle.net/1721.1/103617
https://orcid.org/0000-0001-6988-4260
https://orcid.org/0000-0003-3214-4554
https://orcid.org/0000-0003-3916-6115

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