Characterization of the expression of the pro-metastatic MenaINV isoform during breast tumor progression
Several functionally distinct isoforms of the actin regulatory Mena are produced by alternative splicing during tumor progression. Forced expression of the Mena[superscript INV] isoform drives invasion, intravasation and metastasis. However, the abundance and distribution of endogenously expressed M...
Main Authors: | Rohani, Nazanin, Moufarrej, Mira N., Jones, Joan G., Condeelis, John S., Gertler, Frank B., Oudin, Madeleine Julie, Gertler, Frank, Hughes-Alford, Shannon Kay, Lauffenburger, Douglas A |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
Springer Netherlands
2016
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Online Access: | http://hdl.handle.net/1721.1/103617 https://orcid.org/0000-0001-6988-4260 https://orcid.org/0000-0003-3214-4554 https://orcid.org/0000-0003-3916-6115 |
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