Applications of genome editing for disease modeling in mice

Applications of genome editing for disease modeling in mice

Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, February 2016.

Sonraí bibleagrafaíochta
Príomhchruthaitheoir:	Platt, Randall Jeffrey
Rannpháirtithe:	Feng Zhang.
Formáid:	Tráchtas
Teanga:	eng
Foilsithe / Cruthaithe:	Massachusetts Institute of Technology 2016
Ábhair:	Biological Engineering.
Rochtain ar líne:	http://hdl.handle.net/1721.1/103695

Míreanna comhchosúla

Development of an inducible transcriptional control system in plasmodium falciparum with applications to targeted genome editing
de réir: Wagner, Jeffrey C. (Jeffrey Charles)
Foilsithe / Cruthaithe: (2014)

Therapeutic genome editing: prospects and challenges
de réir: Cox, David Benjamin Turitz, et al.
Foilsithe / Cruthaithe: (2016)

Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions
de réir: Virginie Deleuze, et al.
Foilsithe / Cruthaithe: (2023-09-01)

Genome editing is induced in a binary manner in single human cells
de réir: Gou Takahashi, et al.
Foilsithe / Cruthaithe: (2022-12-01)

Efficient CRISPR/Cas9-mediated genome editing in P. falciparum
de réir: Zhang, Feng, et al.
Foilsithe / Cruthaithe: (2015)

Cyanobacterial type I CRISPR-Cas systems: distribution, mechanisms, and genome editing applications
de réir: Yongjiu Zhang, et al.
Foilsithe / Cruthaithe: (2025-02-01)

CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling
de réir: Chen, Sidi, et al.
Foilsithe / Cruthaithe: (2016)

Engineering of Zinc Finger Nucleases Through Structural Modeling Improves Genome Editing Efficiency in Cells
de réir: Shota Katayama, et al.
Foilsithe / Cruthaithe: (2024-06-01)

A non-viral genome editing platform for site-specific insertion of large transgenes
de réir: Chaudhari, Namrata, et al.
Foilsithe / Cruthaithe: (2021)

Tips, Tricks, and Potential Pitfalls of CRISPR Genome Editing in Saccharomyces cerevisiae
de réir: Jacob S. Antony, et al.
Foilsithe / Cruthaithe: (2022-05-01)

TIGER: Single-step in vivo genome editing in a non-traditional rodent
de réir: Sha Li, et al.
Foilsithe / Cruthaithe: (2023-08-01)

DNA alkylation repair deficient mice are susceptible to chemically induced Inflammatory Bowel Disease
de réir: Green, Stephanie Lauren
Foilsithe / Cruthaithe: (2006)

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
de réir: Yin, Hao, et al.
Foilsithe / Cruthaithe: (2019)

Recombination machinery engineering for precise genome editing in methylotrophic yeast Ogataea polymorpha
de réir: Jiaoqi Gao, et al.
Foilsithe / Cruthaithe: (2021-03-01)

A rapid, flexible and scalable DNA assembly platform for genome engineering and regulated gene expression applications in Plasmodium falciparum
de réir: Nasamu, Armiyaw Sebastian
Foilsithe / Cruthaithe: (2016)

Microinjection for precision genome editing in Caenorhabditis elegans
de réir: Krishna S. Ghanta, et al.
Foilsithe / Cruthaithe: (2021-09-01)

Genome Editing in Medicine: Tools and Challenges
de réir: Gunda Petraitytė, et al.
Foilsithe / Cruthaithe: (2021-08-01)

Protocol for CRISPR-Cas9-mediated genome editing to study spermatogenesis in Caenorhabditis elegans
de réir: Peng Wang, et al.
Foilsithe / Cruthaithe: (2023-12-01)

Citrobacter rodentium induced liver changes in C57BL/6 mice : animal model of acute inflammatory stress and injury
de réir: Raczynski, Arkadiusz R. (Arkadiusz Roland)
Foilsithe / Cruthaithe: (2011)

Engineered IscB-ωRNA system with improved base editing efficiency for disease correction via single AAV delivery in mice
de réir: Ruochen Guo, et al.
Foilsithe / Cruthaithe: (2024-11-01)

Bacterial genes and genome dynamics in the environment
de réir: Timberlake, Sonia C
Foilsithe / Cruthaithe: (2013)

Network analyses for functional genomic screens in cancer
de réir: Wilson, Jennifer L. (Jennifer Lynn)
Foilsithe / Cruthaithe: (2016)

Expanding the limits of Scale and sensitivity in microbial genomics
de réir: Lagoudas, Georgia Kerasia
Foilsithe / Cruthaithe: (2019)

Genome editing of FTR42 improves zebrafish survival against virus infection by enhancing IFN immunity
de réir: Zi-Ling Qu, et al.
Foilsithe / Cruthaithe: (2024-04-01)

Efficient CRISPR-Cas9-mediated genome editing for characterization of essential genes in Trypanosoma cruzi
de réir: Gisele Fernanda Assine Picchi-Constante, et al.
Foilsithe / Cruthaithe: (2022-06-01)

Differential RNA editing landscapes in host cell versus the SARS-CoV-2 genome
de réir: Małgorzata Kurkowiak, et al.
Foilsithe / Cruthaithe: (2023-11-01)

Advancements in gene editing technologies for probiotic-enabled disease therapy
de réir: Lixuan Wang, et al.
Foilsithe / Cruthaithe: (2024-09-01)

Genome Editing Technology and Its Application to Metabolic Engineering in Rice
de réir: Satoru Sukegawa, et al.
Foilsithe / Cruthaithe: (2022-04-01)

Gene editing tools for mycoplasmas: references and future directions for efficient genome manipulation
de réir: Gang Zhao, et al.
Foilsithe / Cruthaithe: (2023-05-01)

High-throughput genomic phenotyping
de réir: Ericksen, Daniel S. (Daniel Southwick), 1977-
Foilsithe / Cruthaithe: (2005)

Engineered CBEs based on Macaca fascicularis A3A with improved properties for precise genome editing
de réir: Chun-Yan Ren, et al.
Foilsithe / Cruthaithe: (2024-03-01)

Protocol for targeted modification of the rice genome using base editing
de réir: Meixia Wang, et al.
Foilsithe / Cruthaithe: (2022-12-01)

Mitotic homologous recombination at engineered repeats in S. cerevisiae and in novel transgenic mice
de réir: Hendricks, Carrie A. (Carrie Anne), 1975-
Foilsithe / Cruthaithe: (2006)

Fluorescent detection of homologous recombination reveals the impact of genetic, physiological, and environmental factors on genomic stability
de réir: Sukup Jackson, Michelle R
Foilsithe / Cruthaithe: (2013)

Large-scale single-cell cloning of genome-edited cultured human cells by On-chip SPiS
de réir: Gou Takahashi, et al.
Foilsithe / Cruthaithe: (2023-09-01)

Rapid genome editing by CRISPR-Cas9-POLD3 fusion
de réir: Ganna Reint, et al.
Foilsithe / Cruthaithe: (2021-12-01)

The impact of age, exposure and genetics on homologous recombination at the engineered repeat sequence in mice
de réir: Wiktor-Brown, Dominika M
Foilsithe / Cruthaithe: (2008)

Computational modeling of protein-biomolecule interactions with application to mechanotransduction and antibody maturation
de réir: Zyto, Aurore
Foilsithe / Cruthaithe: (2009)

EVOLUTION OF CRISPR SYSTEM AND THEIR APPLICABILITY TO GENOME EDITING IN BACTERIA
de réir: Iustin Tiberius Tiberius Munteanu
Foilsithe / Cruthaithe: (2022-08-01)

Genome Editing and Its Applications in Model Organisms
de réir: Dongyuan Ma, et al.
Foilsithe / Cruthaithe: (2015-12-01)