A data-driven approach to optimized medication dosing: a focus on heparin

Purpose To demonstrate a novel method that utilizes retrospective data to develop statistically optimal dosing strategies for medications with sensitive therapeutic windows. We illustrate our approach on intravenous unfractionated heparin, a medication which typically considers only patient weigh...

Full description

Bibliographic Details
Main Authors: Danziger, John, Richter, Stefan E., Eche, Ifeoma M., Chen, Tszyi W., Ghassemi, Mohammad Mahdi, Celi, Leo Anthony G.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Springer Berlin Heidelberg 2016
Online Access:http://hdl.handle.net/1721.1/103811
https://orcid.org/0000-0001-5135-8588