An RNA-aptamer-based two-color CRISPR labeling system

The spatial organization and dynamics of chromatin play important roles in essential biological functions. However, direct visualization of endogenous genomic loci in living cells has proven to be laborious until the recent development of CRISPR-Cas9-based chromatin labeling methods. These methods r...

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Bibliographic Details
Main Authors: Wang, Siyuan, Su, Jun-Han, Zhang, Feng, Zhuang, Xiaowei
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:en_US
Published: Springer Nature 2016
Online Access:http://hdl.handle.net/1721.1/103876
https://orcid.org/0000-0003-2782-2509