Poised Chromatin at the ZEB1 Promoter Enables Breast Cancer Cell Plasticity and Enhances Tumorigenicity

The recent discovery that normal and neoplastic epithelial cells re-enter the stem cell state raised the intriguing possibility that the aggressiveness of carcinomas derives not from their existing content of cancer stem cells (CSCs) but from their proclivity to generate new CSCs from non-CSC popula...

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Bibliographic Details
Main Authors: Chaffer, Christine L., Marjanovic, Nemanja D., Lee, Tony, Bell, George, Kleer, Celina G., Reinhardt, Ferenc, D’Alessio, Ana C., Young, Richard A., Weinberg, Robert A., Young, Richard A., Weinberg, Robert A
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/103883
https://orcid.org/0000-0002-0895-3557
https://orcid.org/0000-0001-8855-8647