Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

Eukaryotic cells compartmentalize biochemical processes in different organelles, often relying on metabolic cycles to shuttle reducing equivalents across intracellular membranes. NADPH serves as the electron carrier for the maintenance of redox homeostasis and reductive biosynthesis, with separate c...

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Bibliographic Details
Main Authors: Lewis, Caroline A., Parker, Seth J., Fiske, Brian Prescott, McCloskey, Douglas, Gui, Dan Yi, Green, Courtney R., Feist, Adam M., Vander Heiden, Matthew G., Metallo, Christian M., Vokes, Natalie I., Lewis, Caroline
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/103913
https://orcid.org/0000-0002-6702-4192
https://orcid.org/0000-0003-0130-3428
https://orcid.org/0000-0002-6883-3805