Nucleotide Binding Preference of the Monofunctional Platinum Anticancer-Agent Phenanthriplatin
The monofunctional platinum anticancer agent phenanthriplatin generates covalent adducts with the purine bases guanine and adenine. Preferential nucleotide binding was investigated by using a polymerase stop assay and linear DNA amplification with a 163-base pair DNA double helix. Similarly to cispl...
| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
John Wiley & Sons
2016
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| Online Access: | http://hdl.handle.net/1721.1/103993 https://orcid.org/0000-0002-6801-0198 https://orcid.org/0000-0002-2693-4982 |