Quality score compression improves genotyping accuracy
To the Editor: Most next-generation sequencing (NGS) quality scores are space intensive, redundant and often misleading. In this Correspondence, we recover quality information directly from sequence data using a compression tool named Quartz, rendering such scores redundant and yielding substantial...
Main Authors: | Yu, Yun William, Yorukoglu, Deniz, Peng, Jian, Berger Leighton, Bonnie |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Language: | en_US |
Published: |
Springer Nature
2016
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Online Access: | http://hdl.handle.net/1721.1/104079 https://orcid.org/0000-0002-8275-9576 https://orcid.org/0000-0003-2315-0768 https://orcid.org/0000-0002-2724-7228 |
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