Downstream reactions and engineering in the microbially reconstituted pathway for Taxol

Taxol (a trademarked product of Bristol-Myers Squibb) is a complex isoprenoid natural product which has displayed potent anticancer activity. Originally isolated from the Pacific yew tree (Taxus brevifolia), Taxol has been mass-produced through processes reliant on plant-derived biosynthesis. Recent...

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Bibliographic Details
Main Authors: Jiang, Ming, Stephanopoulos, Gregory, Pfeifer, Blaine A.
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Language:English
Published: Springer-Verlag 2016
Online Access:http://hdl.handle.net/1721.1/104354
https://orcid.org/0000-0001-6909-4568