Experimental design-aided systematic pathway optimization of glucose uptake and deoxyxylulose phosphate pathway for improved amorphadiene production
Artemisinin is a potent antimalarial drug; however, it suffers from unstable and insufficient supply from plant source. Here, we established a novel multivariate-modular approach based on experimental design for systematic pathway optimization that succeeded in improving the production of amorphadie...
Principais autores: | , , , , |
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Outros Autores: | |
Formato: | Artigo |
Idioma: | English |
Publicado em: |
Springer Berlin Heidelberg
2016
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Acesso em linha: | http://hdl.handle.net/1721.1/104360 https://orcid.org/0000-0001-6909-4568 |