A three-dimensional microfluidic tumor cell migration assay to screen the effect of anti-migratory drugs and interstitial flow

Most anti-cancer drug screening assays are currently performed in two dimensions, on flat, rigid surfaces. However, there are increasing indications that three-dimensional (3D) platforms provide a more realistic setting to investigate accurate morphology, growth, and sensitivity of tumor cells to ch...

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Bibliographic Details
Main Authors: Kalchman, Johann, Fujioka, Shingo, Chung, Seok, Kikkawa, Yamato, Mitaka, Toshihiro, Tanishita, Kazuo, Sudo, Ryo, Kamm, Roger Dale
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Springer-Verlag 2016
Online Access:http://hdl.handle.net/1721.1/104639
https://orcid.org/0000-0002-7232-304X