DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme

DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme

Cancer cells can resist the effects of DNA-damaging therapeutic agents via utilization of DNA repair pathways, suggesting that DNA repair capacity (DRC) measurements in cancer cells could be used to identify patients most likely to respond to treatment. However, the limitations of available technolo...

Full description

Bibliographic Details
Main Authors: Kitange, Gaspar J., Gupta, Shiv K., Sarkaria, Jann N., Nagel, Zachary D., Joughin, Brian Alan, Chaim, Isaac Alexander, Mazzucato, Patrizia, Lauffenburger, Douglas A, Samson, Leona D
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: American Association for Cancer Research (AACR) 2016
Online Access:http://hdl.handle.net/1721.1/105169
https://orcid.org/0000-0003-1787-046X
https://orcid.org/0000-0002-7112-1454

Internet

http://hdl.handle.net/1721.1/105169
https://orcid.org/0000-0003-1787-046X
https://orcid.org/0000-0002-7112-1454

Similar Items