Joint Bayesian inference of risk variants and tissue-specific epigenomic enrichments across multiple complex human diseases

Genome wide association studies (GWAS) provide a powerful approach for uncovering disease-associated variants in human, but fine-mapping the causal variants remains a challenge. This is partly remedied by prioritization of disease-associated variants that overlap GWAS-enriched epigenomic annotations...

詳細記述

書誌詳細
主要な著者: Li, Yue, Kellis, Manolis
その他の著者: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
フォーマット: 論文
言語:en_US
出版事項: Oxford University Press 2016
オンライン・アクセス:http://hdl.handle.net/1721.1/105218