Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope

Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope

Dengue is the most common vector-borne viral disease, causing nearly 400 million infections yearly. Currently there are no approved therapies. Antibody epitopes that elicit weak humoral responses may not be accessible by conventional B cell panning methods. To demonstrate an alternative strategy to...

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Bibliographic Details
Main Authors: Tharakaraman, Kannan, Rowley, Kirk J., Costa, Vivian V., Chan, Kuan Rong, Wong, Yee Hwa, Ong, Li Ching, Tan, Hwee Cheng, Koch, Tyree, Viswanathan, Karthik, Liew, Chong Wai, Tissire, Hamid, Ramakrishnan, Boopathy, Myette, James R., Babcock, Gregory J., Alonso, Sylvie, Lescar, Julien, Shriver, Zachary, Ooi, Eng Eong, Robinson, Luke Nathaniel, Kirloskar, Rama Sanjay, Sasisekharan, Viswanathan, Chen, Jianzhu, Sasisekharan, Ram, Cain, David
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/105266
https://orcid.org/0000-0002-5687-6154
https://orcid.org/0000-0002-2085-7840

Internet

http://hdl.handle.net/1721.1/105266
https://orcid.org/0000-0002-5687-6154
https://orcid.org/0000-0002-2085-7840

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