Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes

Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes

The mechanisms underlying the development of complications in type 1 diabetes (T1D) are poorly understood. Disease modeling of induced pluripotent stem cells (iPSCs) from patients with longstanding T1D(disease duration ≥ 50 years) with severe (Medalist +C) or absent to mild complications (Medalist...

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Bibliographic Details
Main Authors: Bhatt, Shweta, Gupta, Manoj K., Khamaisi, Mogher, Martinez, Rachael, Gritsenko, Marina A., Wagner, Bridget K., Guye, Patrick, Busskamp, Volker, Shirakawa, Jun, Wu, Gongxiong, Liew, Chong Wee, Clauss, Therese R., Valdez, Ivan, El Ouaamari, Abdelfattah, Dirice, Ercument, Takatani, Tomozumi, Keenan, Hillary A., Smith, Richard D., Church, George, Weiss, Ron, Wagers, Amy J., Qian, Wei-Jun, King, George L., Kulkarni, Rohit N.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/105338
https://orcid.org/0000-0003-0396-2443

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http://hdl.handle.net/1721.1/105338
https://orcid.org/0000-0003-0396-2443

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