Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature

Dendrimer-Inspired Nanomaterials for the in Vivo Delivery of siRNA to Lung Vasculature

Targeted RNA delivery to lung endothelial cells has the potential to treat conditions that involve inflammation, such as chronic asthma and obstructive pulmonary disease. To this end, chemically modified dendrimer nanomaterials were synthesized and optimized for targeted small interfering RNA (siRNA...

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Bibliographic Details
Main Authors: Barnes, Carmen M., Khan, Omar Fizal, Zaia, Edmond, Jhunjhunwala, Siddharth, Xue, Wen, Yun, Dong Soo, Dahlman, James, Dong, Yizhou, Pelet, Jeisa, Webber, Matthew, Tsosie, Jonathan, Jacks, Tyler E., Langer, Robert S., Anderson, Daniel Griffith, Cai, Wenxin,M. Arch.Massachusetts Institute of Technology.
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:en_US
Published: American Chemical Society (ACS) 2016
Online Access:http://hdl.handle.net/1721.1/105346
https://orcid.org/0000-0003-3811-2369
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0002-0460-8246
https://orcid.org/0000-0001-5786-0659
https://orcid.org/0000-0003-0624-3532
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0001-5629-4798

Internet

http://hdl.handle.net/1721.1/105346
https://orcid.org/0000-0003-3811-2369
https://orcid.org/0000-0001-8046-2288
https://orcid.org/0000-0002-0460-8246
https://orcid.org/0000-0001-5786-0659
https://orcid.org/0000-0003-0624-3532
https://orcid.org/0000-0001-5785-8911
https://orcid.org/0000-0003-4255-0492
https://orcid.org/0000-0001-5629-4798

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