Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors

The delivery of diagnostic and therapeutic agents to solid tumors is limited by physical transport barriers within tumors, and such restrictions directly contribute to decreased therapeutic efficacy and the emergence of drug resistance. Nanomaterials designed to perturb the local tumor environment w...

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Bibliographic Details
Main Authors: Scherz-Shouval, R., Galie, P. A., Whitesell, L., Chen, C. S., Bagley, Alexander F, Zhang, Angela Q., Wyckoff, Jeffrey, Lindquist, Susan, Bhatia, Sangeeta N
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: American Association for Cancer Research 2016
Online Access:http://hdl.handle.net/1721.1/105476
https://orcid.org/0000-0002-0930-302X
https://orcid.org/0000-0003-2599-2774
https://orcid.org/0000-0003-1307-882X
https://orcid.org/0000-0002-1293-2097