The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy

Stromal cells within the tumor microenvironment are essential for tumor progression and metastasis. Surprisingly little is known about the factors that drive the transcriptional reprogramming of stromal cells within tumors. We report that the transcriptional regulator heat shock factor 1 (HSF1) is f...

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书目详细资料
Main Authors: Scherz-Shouval, Ruth, Santagata, Sandro, Mendillo, Marc L., Sholl, Lynette M., Ben-Aharon, Irit, Beck, Andrew H., Dias-Santagata, Dora, Stemmer, Salomon M., Whitesell, Luke, Koeva, Martina I, Lindquist, Susan
其他作者: Massachusetts Institute of Technology. Department of Biological Engineering
格式: 文件
语言:en_US
出版: Elsevier 2016
在线阅读:http://hdl.handle.net/1721.1/105495
https://orcid.org/0000-0001-7024-0921
https://orcid.org/0000-0003-1307-882X