The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy

The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy

Stromal cells within the tumor microenvironment are essential for tumor progression and metastasis. Surprisingly little is known about the factors that drive the transcriptional reprogramming of stromal cells within tumors. We report that the transcriptional regulator heat shock factor 1 (HSF1) is f...

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Bibliographic Details
Main Authors: Scherz-Shouval, Ruth, Santagata, Sandro, Mendillo, Marc L., Sholl, Lynette M., Ben-Aharon, Irit, Beck, Andrew H., Dias-Santagata, Dora, Stemmer, Salomon M., Whitesell, Luke, Koeva, Martina I, Lindquist, Susan
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/105495
https://orcid.org/0000-0001-7024-0921
https://orcid.org/0000-0003-1307-882X

Internet

http://hdl.handle.net/1721.1/105495
https://orcid.org/0000-0001-7024-0921
https://orcid.org/0000-0003-1307-882X

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