Using simple models to describe the kinetics of growth, glucose consumption, and monoclonal antibody formation in naive and infliximab producer CHO cells

Using simple models to describe the kinetics of growth, glucose consumption, and monoclonal antibody formation in naive and infliximab producer CHO cells

Despite their practical and commercial relevance, there are few reports on the kinetics of growth and production of Chinese hamster ovary (CHO) cells—the most frequently used host for the industrial production of therapeutic proteins. We characterize the kinetics of cell growth, substrate consumptio...

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Bibliographic Details
Main Authors: López-Meza, Julián, Araíz-Hernández, Diana, López-Pacheco, Felipe, Carrillo-Cocom, Leydi Maribel, Rocha-Pizaña, María del Refugio, Alvarez, Mario Moises
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Springer Netherlands 2016
Online Access:http://hdl.handle.net/1721.1/105504

Internet

http://hdl.handle.net/1721.1/105504

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