[superscript 19]F-labeling of the adenine H2-site to study large RNAs by NMR spectroscopy

[superscript 19]F-labeling of the adenine H2-site to study large RNAs by NMR spectroscopy

In comparison to proteins and protein complexes, the size of RNA amenable to NMR studies is limited despite the development of new isotopic labeling strategies including deuteration and ligation of differentially labeled RNAs. Due to the restricted chemical shift dispersion in only four different nu...

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Bibliographic Details
Main Authors: Sochor, F., Müller, D., Richter, C., Fürtig, B., Schwalbe, H., Silvers, Robert Paul Georg
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Springer Netherlands 2016
Online Access:http://hdl.handle.net/1721.1/105512

Internet

http://hdl.handle.net/1721.1/105512

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