[superscript 19]F-labeling of the adenine H2-site to study large RNAs by NMR spectroscopy
In comparison to proteins and protein complexes, the size of RNA amenable to NMR studies is limited despite the development of new isotopic labeling strategies including deuteration and ligation of differentially labeled RNAs. Due to the restricted chemical shift dispersion in only four different nu...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer Netherlands
2016
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| Online Access: | http://hdl.handle.net/1721.1/105512 |