A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways

Chaperones are abundant cellular proteins that promote the folding and function of their substrate proteins (clients). In vivo, chaperones also associate with a large and diverse set of cofactors (cochaperones) that regulate their specificity and function. However, how these cochaperones regulate pr...

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Bibliographic Details
Main Authors: Taipale, Mikko, Krykbaeva, Irina, Lin, Zhen-Yuan, Larsen, Brett, Choi, Hyungwon, Gingras, Anne-Claude, Tucker, George Jay, Peng, Jian, Berger, Bonnie A., Lindquist, Susan
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/105723
https://orcid.org/0000-0003-1307-882X

Internet

http://hdl.handle.net/1721.1/105723
https://orcid.org/0000-0003-1307-882X

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