Spatial reconstruction of single-cell gene expression data

Spatial localization is a key determinant of cellular fate and behavior, but methods for spatially resolved, transcriptome-wide gene expression profiling across complex tissues are lacking. RNA staining methods assay only a small number of transcripts, whereas single-cell RNA-seq, which measures glo...

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Bibliographic Details
Main Authors: Satija, Rahul, Farrell, Jeffrey A, Gennert, David, Schier, Alexander F, Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/105746
https://orcid.org/0000-0001-8567-2049