Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System

The microbial adaptive immune system CRISPR mediates defense against foreign genetic elements through two classes of RNA-guided nuclease effectors. Class 1 effectors utilize multiprotein complexes, whereas Class 2 effectors rely on single-component effector proteins such as the well-characterized Ca...

书目详细资料
Main Authors:	Makarova, Kira S., van der Oost, John, Koonin, Eugene V., Zetsche, Bernd, Gootenberg, Jonathan S, Abudayyeh, Omar Osama, Slaymaker, Ian, Essletzbichler, Patrick, Volz, Sara E., Joung, Julia, Regev, Aviv, Zhang, Feng
其他作者:	Harvard University--MIT Division of Health Sciences and Technology
格式:	文件
语言:	en_US
出版:	Elsevier 2016
在线阅读:	http://hdl.handle.net/1721.1/105747 https://orcid.org/0000-0002-7979-3220 https://orcid.org/0000-0001-8794-2137 https://orcid.org/0000-0001-6656-5002 https://orcid.org/0000-0001-8567-2049 https://orcid.org/0000-0003-2782-2509

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