Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

Extensive cellular heterogeneity exists within specific immune-cell subtypes classified as a single lineage, but its molecular underpinnings are rarely characterized at a genomic scale. Here, we use single-cell RNA-seq to investigate the molecular mechanisms governing heterogeneity and pathogenicit...

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Bibliographic Details
Main Authors: Gaublomme, Jellert T., Yosef, Nir, Lee, Youjin, Gertner, Rona S., Yang, Li V., Wu, Chuan, Pandolfi, Pier Paolo, Mak, Tak, Satija, Rahul, Kuchroo, Vijay K., Park, Hongkun, Regev, Aviv, Shalek, Alexander K
Other Authors: Institute for Medical Engineering and Science
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/105774
https://orcid.org/0000-0001-8567-2049

Internet

http://hdl.handle.net/1721.1/105774
https://orcid.org/0000-0001-8567-2049

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