Transcriptome-scale RNase-footprinting of RNA-protein complexes

Ribosome profiling is widely used to study translation in vivo, but not all sequence reads correspond to ribosome-protected RNA. Here we describe Rfoot, a computational pipeline that analyzes ribosomal profiling data and identifies native, nonribosomal RNA-protein complexes. We use Rfoot to precisel...

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Bibliographic Details
Main Authors: Ji, Zhe, Song, Ruisheng, Huang, Hailiang, Regev, Aviv, Struhl, Kevin
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Nature Publishing Group 2016
Online Access:http://hdl.handle.net/1721.1/105781
https://orcid.org/0000-0001-8567-2049