The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones
Protein AMPylation by Fic domain-containing proteins (Fic proteins) is an ancient and conserved post-translational modification of mostly unexplored significance. Here we characterize the Caenorhabditis elegans Fic protein FIC-1 in vitro and in vivo. FIC-1 is an AMPylase that localizes to the nuclea...
| Main Authors: | , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | en_US |
| Published: |
Public Library of Science
2016
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| Online Access: | http://hdl.handle.net/1721.1/105785 https://orcid.org/0000-0001-5338-0973 https://orcid.org/0000-0001-6819-8832 https://orcid.org/0000-0001-8012-1512 https://orcid.org/0000-0002-1090-6071 |