De Novo Reconstruction of Adipose Tissue Transcriptomes Reveals Long Non-coding RNA Regulators of Brown Adipocyte Development

Brown adipose tissue (BAT) protects against obesity by promoting energy expenditure via uncoupled respiration. To uncover BAT-specific long non-coding RNAs (lncRNAs), we used RNA-seq to reconstruct de novo transcriptomes of mouse brown, inguinal white, and epididymal white fat and identified ∼1,500...

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Bibliographic Details
Main Authors: Bai, Zhiqiang, Xu, Dan, Yuan, Bingbing, Lo, Kinyui Alice, Yoon, Myeong Jin, Lim, Yen Ching, Knoll, Marko, Chen, Shuai, Chen, Peng, Sun, Lei, Alvarez, Juan Rene, Slavov, Nikolai G, Lodish, Harvey F
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: Elsevier 2016
Online Access:http://hdl.handle.net/1721.1/105804
https://orcid.org/0000-0003-2035-1820
https://orcid.org/0000-0002-7029-7415